🧬 New Structure Gallery Added: eIF4E–4EGI1 Complex (PDB 4TPW)
I’ve added a new interactive visualization page for the published protein structure 4TPW, showcasing the eIF4E cap-binding protein in complex with the small-molecule inhibitor 4EGI‑1.
This allosteric complex disrupts eIF4E’s interaction with eIF4G, highlighting a therapeutic mechanism in cancer-related translation initiation. The ligand structure and binding mode are displayed with clarity using an embedded 3D viewer.
🔗 Explore the interactive structure here:
https://evanspap.github.io/Published_Structures/4TPW.html
💬 Also shared on LinkedIn:
https://www.linkedin.com/feed/update/urn:li:share:7346026484299436032/
Feel free to explore and let me know your thoughts or suggestions for future structural uploads!
#StructuralBiology #ProteinStructures #DrugDiscovery #eIF4E #4EGI1 #NGLviewer #CancerResearch #OpenScience
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